MINNEAPOLIS —gs exactly what they needed for a victorious debut by their new quarterback.The throws Cousins made in tight coverage at important times were on target. Unlike Jimmy Garoppolo Brett Favre Jersey , he kept the ball out of the other team’s hands.Cousins passed for two touchdowns and the Vikings forced four turnovers, fueling a 24-16 win over the San Francisco 49ers on Sunday that stuck Garoppolo with his first loss in eight games as an NFL starting quarterback.10<button class="view-gallery">View Gallery</button> Gallery:PHOTOS: Vikings vs. 49ersCousins connected with Stefon Diggs in the second quarter and Kyle Rudolph in the third quarter for scores, and the defense finished the job with three sacks and three second-half interceptions of Garoppolo. Mike Hughes turned one pick into a 28-yard touchdown return, the first by a rookie in a Vikings season opener.“I’m so grateful for this opportunity that I’ve been given, and I just want to make good on it with every chance I get,” said Cousins, who had no turnovers.Harrison Smith sealed the game with an interception with 1:35 left . He also recovered a fumble by Alfred Morris at the 2-yard line after Linval Joseph stripped the ball just in front of the goal line in the late in the first half and sacked Garoppolo on a third-down safety blitz late in the fourth quarter .“It was pretty smooth sailing there for a while,” Vikings coach Mike Zimmer said Adam Thielen Jersey , “and it was good to find the fight and the heart that we had there at the end.”More Vikings coveragePhotos of the Week: 7/21/19 – 7/27/19Rookie Bradbury is central figure to Vikings’ overhauled offensive lineVikings depth at cornerback being tested, Hughes still not clearedPlayers to watch at Minnesota Vikings 2019 training campTop Tweets: Vikings WR Diggs makes push for All-NFL Style TeamGaroppolo finished 15 for 33 for 261 yards and a touchdown pass to rookie Dante Pettis late in the third quarter. With an injury depleted offensive line in front of him and the absence of top wide receiver Marquise Goodwin, Garoppolo was unable to capitalize on the opportunity for a comeback after the 49ers defense forced three straight three-and-out possessions by the Vikings to start the fourth quarter. DeForest Buckner had 2½ sacks for San Francisco.“We knew it was going to be a tough challenge with the environment, going against a tough team,” Garoppolo said. “They stood up to everything we thought they would, but with all the things that went bad we still had a shot at the end there. Just a tough way to end it.”Cousins went 20 for 36 for 244 yards, targeting Adam Thielen 12 times. Thielen caught six passes for 102 yards.“He played the way he always does,” said cornerback Richard Sherman Stefon Diggs Jersey , who made his 49ers debut. “Efficient. Doesn’t make a lot of mistakes. He’s poised and doesn’t get rattled.”Vikings running back Dalvin Cook caught six passes for 55 yards. He said Cousins was “locked in” from the start.“I like to see a guy next to me with that look in his eyes,” Cook said.TOO KITTLE TOO LATETight end George Kittle had five catches for 90 yards, but the one he didn’t make for the 49ers stood out. Wide open after beating Anthony Barr up the seam, Kittle had what would’ve been a 30-yard completion fall off his fingers at midfield. The third-down interception by Hughes came next to give the Vikings a 17-3 lead.“Misjudged it,” Kittle said. “Thought it was a little closer to me. Probably ran a bit too far with my arms out. Just a bad play.”MINNESOTA MEMORIESFred Zamberletti, the team’s original athletic trainer who died last week at age 86, was honored with a pregame moment of silence. The Vikings also staged a 20th anniversary tribute to the 1998 squad that went 15-1 and reached the NFC championship game. Robert Smith, one of 28 former players who were introduced at halftime Harrison Smith Jersey , received the loudest ovation. He focused on the current team at the end of his speech.“We want to see them accomplish something that we weren’t able to do,” Smith told the crowd, “and we want them to do it for you.”INJURY REPORT49ers: Goodwin hurt his right quadriceps in the first quarter and didn’t return. … RG Mike Person went down in the second quarter. His replacement Joshua Garnett was hurt in the third quarter, both with left foot injuries. With three backups on the OL already inactive, rookie Mike McGlinchey moved from RT to RG for the first time in his life while Garry Gilliam took over at RT … With two starters at LB already out, Malcolm Smith (hamstring) and Reuben Foster (suspension), Smith’s sub, Brock Coyle Dru Samia Minnesota Vikings Jerseys , suffered a concussion in the fourth quarter and needed several minutes to get up.Vikings: CB Trae Waynes hurt his right knee while ripping a deep pass away from Pettis in the end zone in the second quarter and didn’t return. With Mackensie Alexander (ankle) inactive and Terence Newman retired, the Vikings had SS Jayron Kearse in slot coverage in the nickel defense with Hughes on the outside for Waynes.UP NEXT49ers: Host Detroit next Sunday. They haven’t lost to the Lions at home since 1975, a streak of 12 straight wins.Vikings: Play at Green Bay next Sunday. They haven’t faced the Packers on the road in September since the 2008 season opener.